For Doctors

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Whole Genome 

Sequencing Technology

 

Sequences data from 23 pairs of chromosomes to detect trisomies,

sex chromosome abnormalities and selected deletions.

SIMPLE: Requires a minimum of 10 ml of maternal blood - paternal blood is not required for the iGene® NIPT test.

 

 

DETECTION OF T21, T18, T13: iGene® NIPT can detect Down Syndrome (T21), Edward Syndrome (T18) and Patau Syndrome (T13)[1].

 

 

TURNAROUND TIME: Turnaround time for results is between 7 to 10 working days upon receipt of the blood sample in the laboratory.

iGene® NIPT is powered by BGI Technology

iGene® NIPT is powered by BGI Technology

Accredited Laboratory

iGene
® NIPT is tested at iGene Laboratory, a molecular diagnostics laboratory in Singapore, accredited by the College of American Pathologists (CAP) and licensed by the Ministry of Health (Singapore) as a Clinical Laboratory (License Number: 17I0382/02/192).

Quality Standards

iGene Laboratory participates in proficiency testing under the international External Quality Assessments (EQA) from CAP and GenQA (formerly known as UK NEQAS), to ensure reliable results. 

Ordering iGene® NIPT

1

Complete Request Form

Please go through the iGene® NIPT Consent Form with your patient and complete the iGene® NIPT Request & Consent Form. Pre-test and Post-test counselling is recommended. 

2

Collect Blood Sample

Draw a minimum of 10 ml of patient's blood (21G needle recommended) into a Streck Tube vacutainer, then place the Streck Tube into the biohazard bag and send it to iGene Laboratory. Turnaround time for sample processing is between 7 to 10 working days from receipt of sample in the laboratory.

 

Note: Do not chill the Streck Tube.

3

Receive Report

When you receive your patient’s report, it is reported as “Screen Negative” or “Screen Positive”.

 

If the result is “Screen Positive”, it is recommended that your patient undergo further confirmatory by diagnostics testing such as amniocentesis, which is an invasive test[2]. This is because iGene® NIPT is a screening and not a diagnostic test.

iGene® NIPT is powered by BGI Technology

Frequently Asked Questions (FAQs)

Module 1: Introduction to Big Data


Session 1: Introduction to Big Data

Session 2: Business application of Big Data

Session 3: Technologies for handling Big Data

Session 4: Understanding the Hadoop 2 Ecosystem

Session 5: Frameworks for Processing on Hadoop – MapReduce and YARN




Module 2: Understanding Analytics


Session 1: Understanding Analytics

Session 2: Analytical tools

Session 3: Exploring R

Session 4: Reading datasets into R, Exporting data from R

Session 5: Manipulating and Processing Data in R




Module 3: Data Analysis using R


Session 1: Using functions and packages in R

Session 2: Descriptive statistics in R

Session 3: Analysing data using functions, loops, and data frames, introducing Rhadoop

Session 4: Graphical analysis in R

Session 5: Hypothesis testing in R

Session 6: Statistical analysis on massive scale – Rhadoop and Mahout




Module 4: Big Data Analytics Methods


Session 1: Implementing a Big Data Solution

Session 2: Data Cleaning and Pre-processing

Session 3: Social Media Analytics and Text Mining

Session 4: Mobile Analytics

Session 5: Big Data Visualizations




Module 5: Machine Learning Foundations


Session 1: Introduction to Machine Learning

Session 2: Linear Regression

Session 3: Non-linear Regression

Session 4: Graphical Models and Bayesian Network

Session 5: Decision Trees




Module 6: Advance Machine Learning


Session 1: Cluster Analysis

Session 2: Artificial Neural Networks

Session 3: Support Vector Machine

Session 4: Time Series




Module 7: Big Data Analytics – Technologies and Tools


Session 1: Storing Data in Hadoop 2 HDFS

Session 2: Working with MapReduce on YARN

Session 3: Working with YARN

Session 4: Exploring Hive

Session 5: Advanced Querying with Hive

Session 6: Analysing Data with Pig




Bonus Session


  • Spark and Scala Fundamentals
  • Typical Interview Questions
  • Case Studies:
    • Big Data Business Problems and Solutions – Telecom Industry
    • Big Data Business Problems and Solutions – Insurance Fraud Analytics
    • Big Data Business Problems and Solutions – Credit Risk
    • Big Data Business Problems and Solutions – Online Customer Segmentation
    • Big Data Business Problems and Solutions – Use of Visualization Tools in e-commerce





Reference:

1. Zhang H, et al. (2015) Ultrasound Obstet. & Gynecol. 10.1002/uog/14792.

2. Gregg, A. R., et al. (2016). Noninvasive prenatal screening for fetal aneuploidy, 2016 update: A position statement of the American College of Medical Genetics and Genomics. Genetics in Medicine. doi:10.1038/gim.2016.97

 

iGene® NIPT is powered by BGI Technology